Development of Application Technology for Multi-Peptide Concentration and Desolventization by Scraped Surface Evaporation

Process Description:
First, the raw material solution is transported to the feed tank. The raw liquid stored in the raw material tank is then transported to the raw material preheater via vacuum differential pressure or feed pump, and after preheating, it enters the thin film evaporator. Inside the evaporator, the raw liquid is heated and evaporated under vacuum conditions. The vapor phase is discharged from the light phase outlet, condensed through two condensers, and then enters the light phase tank. Once a certain liquid level is reached, it is continuously discharged through the light phase pump. The unevaporated heavy phase flows along the inner wall of the evaporator to the bottom and enters the heavy phase receiving tank. When a certain liquid level is reached, it is continuously discharged through the heavy phase discharge pump. This process achieves vacuum thin film separation of the material.

The feed section can achieve precise control of the feed volume through flow meters, control valves, and variable frequency feed pumps, with an error range of ≤1%. The evaporation section is controlled by variable frequency rotation of the scraper to ensure uniform film distribution and stable evaporation. The vapor phase is condensed through two stages of condensers to ensure complete condensation and minimize material loss. The liquid levels in the light phase and heavy phase tanks are interconnected with the discharge pumps to ensure continuous and stable discharge. High-vacuum discharge pumps are used to ensure smooth discharge under vacuum conditions. The vacuum system can be adjusted to the desired vacuum level, ranging from 15Pa to 1KPa. The feed volume, vacuum level, and temperature are interconnected to ensure the quality of the heavy phase components. Multiple temperature sensors, pressure sensors, flow sensors, and level sensors are installed at various locations in the system to accurately monitor the operating temperature, pressure, level, and feed volume. The entire system can operate fully automatically without human intervention.

Skid Composition:
Considering factors such as transportation, lifting, and site use, the skid dimensions are: 3500mm (length) × 3500mm (width) × 2000mm (height).

Application Scenarios:
Scraped surface evaporators are widely used in industries such as petroleum, chemical, and pharmaceuticals, particularly for high-viscosity materials (such as tannin, honey, etc.) and materials prone to crystallization, scaling, and heat sensitivity.